Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 13/20 | 0.46 |
| ▸ | DRD5 | P21918 | 13/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518485 | 0.88 | DRD1 (0.57) | DRD1DRD5PIK3CDPIK3CAPIK3CG | |
| SCHEMBL3179574 | 0.83 | DRD1 (0.44) | DRD1DRD5PIK3CDPIK3CAPIK3CG | |
| SCHEMBL3179577 | 0.83 | DRD1 (0.44) | DRD1DRD5PIK3CDPIK3CAPIK3CG | |
| SCHEMBL4514027 | 0.82 | DRD1 (0.46) | DRD1DRD5PIK3CDPIK3CAPIK3CG | |
| SCHEMBL4531450 | 0.80 | DRD1 (0.45) | DRD1DRD5PIK3CDPIK3CAPIK3CG | |
| SCHEMBL4515104 | 0.78 | DRD1 (0.41) | DRD1DRD5 | |
| SCHEMBL1997653 | 0.76 | CDK1 (0.41) | SMN1; SMN2GRM1 | |
| SCHEMBL4421685 | 0.75 | DRD1 (0.51) | DRD1DRD5SMN1; SMN2GRM1 | |
| SCHEMBL4791071 | 0.75 | DRD1 (0.37) | DRD1DRD5PIK3CDPIK3CAPIK3CG | |
| SCHEMBL4413685 | 0.74 | DRD1 (0.52) | DRD1DRD5SMN1; SMN2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121036-A2 | SUBSTITUTED ARYL PYRIMIDINONE DERIVATIVES | NEUROGEN CORPORATION (US) | 2009-10-01 | — | — | WO | claimed |