Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615711 | 0.89 | CNR1 (0.82) | CNR1CNR2 | |
| SCHEMBL3628024 | 0.88 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL3625798 | 0.82 | CNR1 (0.75) | CNR1CNR2 | |
| SCHEMBL3479342 | 0.81 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL3482043 | 0.79 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL3622532 | 0.79 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL3627816 | 0.77 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL5359447 | 0.76 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL5296762 | 0.76 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL3624318 | 0.76 | CNR1 (0.85) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682550-B1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | MERCK & CO INC (US) | 2009-12-23 | — | — | EP | disclosed |
| EP-1682550-A4 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | MERCK & CO INC (US) | 2007-01-03 | — | — | EP | disclosed |
| CN-1875021-A | Substituted naphthyridinone derivatives | MERCK & CO INC (US) | 2006-12-06 | — | — | CN | disclosed |
| EP-1682550-A1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | Merck & Co., Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005047285-A1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | MERCK & CO., INC. (US) | 2005-05-26 | — | — | WO | disclosed |