SCHEMBL44131

SCHEMBL44131

[O]N1C(=O)CCC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9643829 0.85
SCHEMBL1491907 0.64
SCHEMBL12360461 0.64 BRD4 (0.43)
SCHEMBL48363 0.64
SCHEMBL4011609 0.64 BRD4 (0.30)
SCHEMBL2201542 0.64
SCHEMBL9020270 0.64
SCHEMBL18779 0.64
SCHEMBL375535 0.64
SCHEMBL58 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2223 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197924-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-06-20 US claimed
US-12011485-B2 Sulfomaleimide-based linkers and corresponding conjugates PIERRE FABRE MEDICAMENT (FR) 2024-06-18 US claimed
CN-118047832-A Anti-MET antibodies that bind MET, bispecific antigen binding molecules, and methods of use thereof 瑞泽恩制药公司 2024-05-17 CN claimed
US-20240115719-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME AJINOMOTO CO., INC. (JP) 2024-04-11 US claimed
EP-4337194-A1 POLYMER CONJUGATES OF DRUGS TARGETING 5-HT AND OTHER RECEPTORS IN THE CENTRAL NERVOUS SYSTEM (CNS) THAT ALSO TARGET RECEPTORS OUTSIDE OF THE CNS Arbormentis LLC (US) 2024-03-20 EP claimed
CN-117693338-A Polymer conjugates of drugs targeting 5-HT and other receptors in the Central Nervous System (CNS) and also targeting receptors outside the CNS 阿伯门蒂斯有限责任公司 2024-03-12 CN claimed
CN-115109083-B Pyridostatin compound, preparation method and application thereof, and pharmaceutical composition 中国科学院长春应用化学研究所 2024-02-13 CN claimed
EP-4306535-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED USING SAME AJINOMOTO CO., INC. (JP) 2024-01-17 EP claimed
EP-3309552-B1 DYE COMPOUND SFC CO LTD (KR) 2024-01-17 EP claimed
US-20240000965-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME AJINOMOTO CO., INC. (JP) 2024-01-04 US claimed
EP-0074306-B1 ANTI-VIRAL GUANINE DERIVATIVES MERCK & CO. INC. (US) 1988-06-01 EP claimed
EP-0264797-A2 Benzodiazepines assay, tracers, immunogens and antibodies ABBOTT LABORATORIES (US) 1988-04-27 EP claimed
US-4680338-A Bifunctional linker IMMUNOMEDICS, INC. (US) 1987-07-14 US claimed
EP-0220899-A1 Bifunctional linker Immunomedics, Inc. (US) 1987-05-06 EP claimed
EP-0165164-A1 Anti-viral compounds, their preparation and anti-viral compositions MERCK & CO. INC. (US) 1985-12-18 EP claimed
EP-0104461-A2 Process for preparing antihypertensive 1-substituted cyclic lactam-2-carboxylic acids and their derivatives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-04 EP claimed
US-4439364-A Process for preparing antihypertensive 1-substituted cyclic lactam-2-carboxylic acids and their derivatives E. I. DU PONT DE NEMOURS & COMPANY (US) 1984-03-27 US claimed
US-4156081-A IMMUNOASSAYING SYVA COMPANY (US) 1979-05-22 US claimed
US-4145549-A CYCLIZATION, SOLVOLYSIS SANDOZ LTD. (CH) 1979-03-20 US claimed
US-4000139-A ERGOT ALKALOID INTERMEDIATES SANDOZ LTD. (CH) 1976-12-28 US claimed