SCHEMBL4413243

SCHEMBL4413243

Cc1ccc(C2CCC(C3CCC(CCC(F)(F)F)CC3)CC2)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 19/20 0.39
NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17616147 0.90 OPRL1 (0.38) OPRL1NOTUM
SCHEMBL17616125 0.86 OPRL1 (0.40) OPRL1NOTUM
SCHEMBL4406898 0.86 OPRL1 (0.40) OPRL1
SCHEMBL12140866 0.86 OPRL1 (0.40) OPRL1
SCHEMBL3437350 0.86 OPRL1 (0.40) OPRL1
SCHEMBL17614851 0.86 OPRL1 (0.40) OPRL1
SCHEMBL12856792 0.84 OPRL1 (0.40) OPRL1
SCHEMBL26802882 0.84 OPRL1 (0.37) OPRL1NOTUM
SCHEMBL12386950 0.83 OPRL1 (0.39) OPRL1
SCHEMBL17616162 0.83 OPRL1 (0.36) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140362335-A1 POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS LC VISION, LLC (US) 2014-12-11 US disclosed
US-8834742-B2 Polymer-doped vertically-aligned nematic liquid crystals CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-09-16 US disclosed
US-20120105791-A1 POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS NATIONAL SCIENCE FOUNDATION 2012-05-03 US disclosed
WO-2012016130-A2 POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2012-02-02 WO disclosed