SCHEMBL4414070

SCHEMBL4414070

O=[PH](OCCCCc1ccccc1)OCCCCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.50
IDO1 P14902 1/20 0.48
FFAR1 O14842 1/20 0.47
MAOA P21397 1/20 0.47
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
HTR2A P28223 1/20 0.45
SIGMAR1 Q99720 1/20 0.44
HDAC3 O15379 1/20 0.44
MAPK1 P28482 1/20 0.44
ADRA1A P35348 1/20 0.44
HDAC4 P56524 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC1 Q13547 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14890565 0.98 MAPT (0.48) MAOBIDO1FFAR1MAOALMNA
SCHEMBL4920782 0.98 MAPT (0.48) MAOBIDO1FFAR1MAOALMNA
SCHEMBL4406119 0.94 IDO1 (0.55) MAOBIDO1FFAR1MAOALMNA
SCHEMBL1101315 0.85 CA1 (0.48) MAOBIDO1FFAR1MAOALMNA
SCHEMBL7434838 0.85 FFAR1 (0.49) MAOBIDO1FFAR1MAOALMNA
SCHEMBL28784998 0.83 MAPT (0.50) MAOBIDO1FFAR1LMNAMAPT
SCHEMBL27522937 0.83 MAPT (0.50) MAOBIDO1FFAR1LMNAMAPT
SCHEMBL28170101 0.82 MAPT (0.49) MAOBIDO1FFAR1LMNAMAPT
SCHEMBL4413671 0.81 TAAR1 (0.45) MAOBIDO1FFAR1MAOAHTR2A
SCHEMBL10773558 0.81 TAAR1 (0.45) MAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978387-A Three-component synthesis method of polyphosphonate 华南理工大学 2025-05-13 CN claimed
CN-119978387-A Three-component synthesis method of polyphosphonate 华南理工大学 2025-05-13 CN disclosed
CN-116685715-A Substrate, selective film deposition method, deposited film of organic substance, and organic substance 中央硝子株式会社 2023-09-01 CN disclosed
US-7635748-B2 Resin and article molded therefrom TORAY INDUSTRIES, INC. (JP) 2009-12-22 US disclosed
CN-100497335-C Optical resolution method substituting oxyphosphonate acetate SHANGHAI MEDICAL INDUSTRY INST (CN) 2009-06-10 CN disclosed
CN-100488969-C Optically active substituted oxyphosphonate salt acetate and its use SHANGHAI MEDICAL INDUSTRY INST (CN) 2009-05-20 CN disclosed
EP-1270646-B1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES (JP) 2008-11-26 EP disclosed
US-20080139778-A1 Resin and article molded therefrom TAKANISHI KEIJIRO 2008-06-12 US disclosed
CN-1955185-A Optical active substitution oxyphosphonate salt acetate and its use SHANGHAI MEDICAL INDUSTRY INST (CN) 2007-05-02 CN disclosed
CN-1955176-A Optical separation method substituting oxyphosphonate acetate SHANGHAI MEDICAL INDUSTRY INST (CN) 2007-05-02 CN disclosed
EP-1270646-A1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES, INC. (JP) 2003-01-02 EP disclosed
EP-0229520-B1 ORALLY ACTIVE PHOSPHONYL HYDROXYACYL PROLINES AND PROCESSES FOR PREPARING PHOSPHONYL HYDROXYACYL PROLINES E.R. Squibb & Sons, Inc. (US) 1990-05-30 EP disclosed
EP-0350138-A2 Processes for preparing phosphonyl hydroxyacyl prolines E.R. SQUIBB & SONS, INC. (US) 1990-01-10 EP disclosed
EP-0097534-B1 PHOSPHONYL HYDROXYACYL AMINO ACID DERIVATIVES AS ANTIHYPERTENSIVES E.R. Squibb & Sons, Inc. (US) 1988-09-21 EP disclosed
US-4703043-A Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive E. R. SQUIBB & SONS, INC. (US) 1987-10-27 US disclosed
EP-0229520-A1 Orally active phosphonyl hydroxyacyl prolines and processes for preparing phosphonyl hydroxyacyl prolines E.R. Squibb & Sons, Inc. (US) 1987-07-22 EP disclosed
US-4616005-A Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives E. R. SQUIBB & SONS, INC. (US) 1986-10-07 US disclosed
EP-0120728-A1 Thiazine and thiazepine containing compounds E.R. Squibb & Sons, Inc. (US) 1984-10-03 EP disclosed
US-4452790-A Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives E. R. SQUIBB & SONS, INC. (US) 1984-06-05 US disclosed
EP-0097534-A2 Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives E.R. Squibb & Sons, Inc. (US) 1984-01-04 EP disclosed