Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 18/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 6/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332323 | 1.00 | SLC5A2 (0.40) | SLC5A2SLC5A1ADRA2ASLC5A11LMNA | |
| SCHEMBL4414321 | 1.00 | SLC5A2 (0.40) | SLC5A2SLC5A1ADRA2ASLC5A11LMNA | |
| SCHEMBL4332319 | 1.00 | SLC5A2 (0.40) | SLC5A2SLC5A1ADRA2ASLC5A11LMNA | |
| SCHEMBL4423604 | 0.92 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL3407894 | 0.92 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL3410079 | 0.92 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL3407900 | 0.92 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL4416146 | 0.88 | CYP11B1 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL3407262 | 0.88 | CYP11B1 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL3407267 | 0.88 | CYP11B1 (0.41) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679966-A4 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-27 | — | — | EP | claimed |
| EP-1679966-A2 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-19 | — | — | EP | claimed |
| WO-2005012242-A2 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2005-02-10 | — | — | WO | claimed |