Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.89 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.89 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.89 |
| ▸ | PREP | P48147 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551023 | 0.94 | DPP4 (1.00) | DPP4DPP8DPP7PREP | |
| SCHEMBL3551018 | 0.94 | DPP4 (1.00) | DPP4DPP8DPP7PREP | |
| SCHEMBL3557003 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP7PREP | |
| SCHEMBL3556999 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP7PREP | |
| SCHEMBL8276351 | 0.85 | DPP4 (0.77) | DPP4DPP8DPP7PREP | |
| SCHEMBL3551457 | 0.81 | DPP4 (0.85) | DPP4DPP8DPP7PREP | |
| SCHEMBL3551456 | 0.81 | DPP4 (0.85) | DPP4DPP8DPP7PREP | |
| SCHEMBL4410302 | 0.80 | DPP4 (0.84) | DPP4DPP8DPP7PREP | |
| SCHEMBL4410305 | 0.80 | DPP4 (0.84) | DPP4DPP8DPP7PREP | |
| SCHEMBL3546283 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1729774-A4 | PYRROLIDINE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-05-06 | — | — | EP | claimed |
| EP-1729774-A1 | PYRROLIDINE COMPOUNDS | National Health Research Institutes (TW) | 2006-12-13 | — | — | EP | claimed |
| WO-2005087235-A1 | PYRROLIDINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (CN) | 2005-09-22 | — | — | WO | claimed |
| EP-1729774-A4 | PYRROLIDINE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-05-06 | — | — | EP | disclosed |
| EP-1729774-A1 | PYRROLIDINE COMPOUNDS | National Health Research Institutes (TW) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005087235-A1 | PYRROLIDINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (CN) | 2005-09-22 | — | — | WO | disclosed |