Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3747524 | 1.00 | MEN1 (0.45) | MEN1KMT2ATLR8KCNH2CYP1A2 | |
| SCHEMBL8225761 | 0.98 | MEN1 (0.46) | MEN1KMT2ATLR8KCNH2CYP1A2 | |
| SCHEMBL2177707 | 0.93 | MEN1 (0.47) | MEN1KMT2ATLR8CYP1A2ERBB2 | |
| SCHEMBL18076729 | 0.92 | TLR8 (0.47) | MEN1KMT2ATLR8KCNH2MAPT | |
| SCHEMBL5749026 | 0.92 | TLR8 (0.45) | MEN1KMT2ATLR8KCNH2CYP1A2 | |
| SCHEMBL5747752 | 0.92 | TLR8 (0.45) | MEN1KMT2ATLR8KCNH2CYP1A2 | |
| SCHEMBL5748158 | 0.92 | TLR8 (0.45) | MEN1KMT2ATLR8KCNH2CYP1A2 | |
| SCHEMBL5746998 | 0.89 | MEN1 (0.40) | MEN1KMT2ATLR8KCNH2CYP1A2 | |
| SCHEMBL5748545 | 0.89 | MEN1 (0.40) | MEN1KMT2ATLR8KCNH2CYP1A2 | |
| SCHEMBL5746682 | 0.89 | MEN1 (0.40) | MEN1KMT2ATLR8KCNH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660638-A4 | LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME | INTEGRAL MOLECULAR INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1660638-A2 | LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME | Integral Molecular, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005042695-A2 | LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME | INTEGRAL MOLECULAR, INC. (US) | 2005-05-12 | — | — | WO | disclosed |