Perflunafene

Perflunafene

SCHEMBL4418110

FC1(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C1(F)F.FC1(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C1(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
TDP1 Q9NUW8 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perflunafene SCHEMBL1069193 1.00 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL1279184 1.00 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL1280184 1.00 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL15755574 1.00 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL10889508 1.00 MEN1 (1.00) MEN1KMT2ATDP1
Perflunafene SCHEMBL63605 1.00 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL2476658 1.00 MEN1 (1.00) MEN1KMT2ATDP1
Perflunafene SCHEMBL63606 1.00 MEN1 (1.00) MEN1KMT2ATDP1
SCHEMBL18979331 0.94 MEN1 (0.89) MEN1KMT2ATDP1
SCHEMBL1771191 0.94 MEN1 (0.89) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106999717-A Onychomycosis treatment apparatus and method 迪维斯法姆有限公司 2017-08-01 CN disclosed
CN-101981180-A Pancreatic islet cell preparation and transplantation BAYLOR RES INST 2011-02-23 CN disclosed
WO-2009149434-A1 METHOD FOR ELIMINATING CARBON DIOXIDE FROM WASTE GASES DRESSLER LAWRENCE V (US) 2009-12-10 WO disclosed
US-5374243-A Oxygen permeable bag containing oxygen-transporting perfluorochemical for providing oxygen internally to mammals ALPHA THERAPEUTIC CORPORATION (US) 1994-12-20 US disclosed
US-4919895-A Saeled container, valve and filter; synthetic blood ALPHA THERAPEUTIC CORPORATION (US) 1990-04-24 US disclosed
US-4769241-A Apparatus and process for oxygenation of liquid state dissolved oxygen-carrying formulation ALPHA THERAPEUTIC CORPORATION (US) 1988-09-06 US disclosed