SCHEMBL441818

SCHEMBL441818

C=CC(=O)OCCC[Si](OC)(OC)OC.[SiH4]

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
ALDH1A1 P00352 5/20 0.57
CYP3A4 P08684 2/20 0.57
HPGD P15428 1/20 0.56
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.40
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HCAR2 Q8TDS4 3/20 0.33
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71730 0.98 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
Methane SCHEMBL28113061 0.96 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28208777 0.96 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
Ethylene SCHEMBL22126280 0.96 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28323519 0.96 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
Acetone SCHEMBL28485433 0.95 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23361362 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL221397 0.93 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28327315 0.93 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
Acrylic Acid SCHEMBL29139304 0.93 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020067046-A1 SEALING AGENT FOR ORGANIC ELECTROLUMINESCENT DISPLAY ELEMENTS デンカ株式会社 2020-04-02 WO disclosed
CN-110383121-A Unilateral protection polarizing coating, image display device and its method for continuous production with adhesive phase 日东电工株式会社 2019-10-25 CN disclosed
CN-106465505-B The manufacturing method of seal 味之素株式会社 2019-09-20 CN disclosed
CN-110249004-A Polyimide precursor composition 东京应化工业株式会社 2019-09-17 CN disclosed
CN-105074907-B The manufacturing method of electronic component encapsulation resin sheet and electron device package body 日东电工株式会社 2019-06-18 CN disclosed
CN-104592745-B Thermoplastic resin composition comprising acrylic modified organic siliconresin 日信化学工业株式会社 2019-04-16 CN disclosed
CN-109476958-A The manufacturing method of bonding agent piece 日本瑞翁株式会社 2019-03-15 CN disclosed
CN-108387954-A The manufacturing method of laminated body, flexible devices and laminated body 东京应化工业株式会社 2018-08-10 CN disclosed
CN-108389512-A The manufacturing method of laminated body, flexible devices and laminated body 东京应化工业株式会社 2018-08-10 CN disclosed
CN-108300364-A Organic conductive layers adhesive phase, adhesive composition, polarizing coating and image display device with adhesive phase 日东电工株式会社 2018-07-20 CN disclosed
CN-107709452-A Resin composition, prepreg, resin sheet, laminate, and printed wiring board 三菱瓦斯化学株式会社 2018-02-16 CN disclosed
CN-107429059-A ENERGY-SENSITIVE RESIN COMPOSITION 东京应化工业株式会社 2017-12-01 CN disclosed
CN-107033795-A Adhesive sheet 琳得科株式会社 2017-08-11 CN disclosed
CN-106465505-A Manufacturing method for sealed body 味之素株式会社 2017-02-22 CN disclosed
CN-105900535-A Insulating layer for printed wiring board and printed wiring board 三菱瓦斯化学株式会社 2016-08-24 CN disclosed
WO-2014088926-A1 D1530 RADIATION CURABLE PRIMARY COATINGS FOR OPTICAL FIBER DSM IP ASSETS BV (NL) 2014-06-12 WO disclosed
US-20120065319-A1 Elastomer Compositions Modified By Silanes DOW CORNING EUROPE SA (BE) 2012-03-15 US disclosed
US-20080199618-A1 Using radiation curable acrylated polysiloxane solution with photoinitiator; waterproofing ARKEMA INC. (US) 2008-08-21 US disclosed
EP-1922154-A2 METHOD OF STRENGTHENING A BRITTLE OXIDE SUBSTRATE WITH A WEATHERABLE COATING Arkema Inc. (US) 2008-05-21 EP disclosed
WO-2007008426-A2 METHOD OF STRENGTHENING A BRITTLE OXIDE SUBSTRATE WITH A WEATHERABLE COATING ARKEMA INC. (US) 2007-01-18 WO disclosed