⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30435074 | 0.80 | — | — | |
| SCHEMBL13916486 | 0.76 | — | — | |
| N-Propyl Bromide SCHEMBL795893 | 0.73 | — | — | |
| SCHEMBL30049452 | 0.73 | — | — | |
| SCHEMBL1075863 | 0.69 | — | — | |
| Tetradecane SCHEMBL30376511 | 0.69 | TSHR (0.57) | — | |
| Nonane SCHEMBL31406078 | 0.67 | — | — | |
| 1-Pentanol SCHEMBL30624686 | 0.67 | — | — | |
| SCHEMBL13916493 | 0.67 | — | — | |
| Hexane SCHEMBL10340649 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404722-B2 | Oxazole compounds compositions and methods of use | AMGEN INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20110060011-A1 | OXAZOLE COMPOUNDS COMPOSITIONS AND METHODS OF USE | AMGEN INC. (US) | 2011-03-10 | — | — | US | disclosed |
| WO-2009151495-A2 | OXAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AMGEN INC. (US) | 2009-12-17 | — | — | WO | disclosed |