SCHEMBL441825

SCHEMBL441825

Nc1cccc(OCCCCOc2cccc(N)c2)c1

nearest known ligand 0.79

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.79
CYP3A4 P08684 2/20 0.67
TP53 P04637 1/20 0.67
MAOB P27338 2/20 0.60
ALDH1A1 P00352 1/20 0.56
APP P05067 1/20 0.55
PRSS1 P07477 6/20 0.53
KCNA3 P22001 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437009 1.00 TSHR (0.79) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL18045584 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL29508345 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL29437011 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL865529 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL5069212 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL18045563 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL18045545 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL867463 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL18045565 0.98 TSHR (0.82) TSHRCYP3A4TP53MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100662-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2026-05-15 WO disclosed
WO-2025033304-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL ALIGNMENT FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-02-13 WO disclosed
WO-2024058164-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2024-03-21 WO disclosed
WO-2023171690-A1 WEAK-ANCHORING LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-09-14 WO disclosed
WO-2023157879-A1 WEAK-ANCHORING LIQUID CRYSTAL ALIGNING AGENT, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-08-24 WO disclosed
WO-2023120726-A1 WEAK-ANCHORING LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CYRSTAL DISPLAY ELEMENT 日産化学株式会社 2023-06-29 WO disclosed
WO-2023048278-A1 WEAKLY ANCHORING LIQUID-CRYSTAL ALIGNMENT AGENT, LIQUID-CRYSTAL DISPLAY ELEMENT, AND POLYMER 日産化学株式会社 2023-03-30 WO disclosed
WO-2022260048-A1 WEAK ANCHORING LIQUID CRYSTAL ALIGNING AGENT, LIQUID CYRSTAL DISPLAY ELEMENT AND COPOLYMER 日産化学株式会社 2022-12-15 WO disclosed
WO-2022196565-A1 LIQUID-CRYSTAL COMPOSITION, LIQUID-CRYSTAL DISPLAY ELEMENT PRODUCTION METHOD, AND LIQUID-CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2022-09-22 WO disclosed
EP-3159737-B1 LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT NISSAN CHEMICAL CORP (JP) 2021-05-26 EP disclosed
US-20120065395-A1 2,4 (4,6) PYRIMIDINE DERIVATIVES FREYNE EDDY JEAN EDGARD (BE) 2012-03-15 US disclosed
US-20100160310-A1 2,4 (4,6) PYRIMIDINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2010-06-24 US disclosed
US-6307002-B1 POLYIMIDES FROM TETRAACIDS AND DIAMINES KANEKA CORPORATION (JP) 2001-10-23 US disclosed
US-6143917-A FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD UBE INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed
US-4935502-A Diazo compounds, a process for their preparation and their use as colorants HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-19 US disclosed
US-4870164-A INTENSE YELLOW PIGMENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-26 US disclosed
US-4769439-A Polyimides and method for making GENERAL ELECTRIC COMPANY (US) 1988-09-06 US disclosed
EP-0024702-B1 DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-16 EP disclosed
EP-0024702-A2 Disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065395-A1 2,4 (4,6) PYRIMIDINE DERIVATIVES NR0B1, NR1H3, NCOA3 TSHR 1119/4885CYP3A4 46/4885TP53 3933/4885
US-20100160310-A1 2,4 (4,6) PYRIMIDINE DERIVATIVES NR1H3, NR1H2, NR0B1 TSHR 1075/4885CYP3A4 64/4885TP53 4147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.