Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792602 | 1.00 | TSHR (0.57) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL445010 | 1.00 | TSHR (0.57) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL445475 | 1.00 | TSHR (0.57) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL3712982 | 0.98 | TSHR (0.60) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL3712986 | 0.98 | TSHR (0.60) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL6722524 | 0.94 | TSHR (0.56) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL443504 | 0.94 | TSHR (0.56) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL6722551 | 0.94 | TSHR (0.56) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL10782636 | 0.90 | TSHR (0.49) | TSHRATMHCAR2PRSS1PRSS2 | |
| SCHEMBL10783818 | 0.90 | TSHR (0.49) | TSHRATMHCAR2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398874-B1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | LUBRIZOL CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |
| EP-2398874-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096291-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |