Chlorobenzene

Chlorobenzene

SCHEMBL4418883

Clc1ccccc1.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
ALDH1A1 P00352 3/20 0.53
TP53 P04637 1/20 0.53
CYP1A2 P05177 3/20 0.52
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
ALOX15 P16050 1/20 0.44
MAPT P10636 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
PPARA Q07869 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NR4A1 P22736 1/20 0.42
HTT P42858 2/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL29172530 0.83 TSHR (0.73) TSHRALDH1A1CYP1A2CES2CES1
Chlorobenzene SCHEMBL27620795 0.83 TSHR (0.73) TSHRALDH1A1CYP1A2CES2CES1
Chlorobenzene SCHEMBL2533883 0.83 TSHR (0.73) TSHRALDH1A1CYP1A2CES2CES1
Chlorobenzene SCHEMBL11116080 0.82 TSHR (0.55) TSHRALDH1A1CYP1A2CES2CES1
Pivalate SCHEMBL27380361 0.82 TSHR (0.55) TSHRCYP1A2CES2CES1ALOX15
Chlorobenzene SCHEMBL28220113 0.81 TSHR (0.61) TSHRALDH1A1CYP1A2CES2CES1
Chlorobenzene SCHEMBL16894006 0.80 TSHR (0.69) TSHRALDH1A1CYP1A2CES2CES1
Chlorobenzene SCHEMBL28956847 0.80 TSHR (0.69) TSHRALDH1A1CYP1A2CES2CES1
Chlorobenzene SCHEMBL27873959 0.80 TSHR (0.69) TSHRALDH1A1CYP1A2CES2CES1
Chlorobenzene SCHEMBL3144821 0.80 TSHR (0.79) TSHRALDH1A1TP53CYP1A2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318043-A1 METHOD FOR MAKING POLYMERIC EXTRUDED COMPOSITE PRODUCTS AND CARBON NANOTUBES NANOLEDGE INC. (CA) 2009-12-24 US disclosed