Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27287754 | 1.00 | S1PR1 (0.57) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL28111758 | 1.00 | S1PR1 (0.57) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL27551089 | 1.00 | S1PR1 (0.57) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| Bromide SCHEMBL28654872 | 0.98 | S1PR1 (0.56) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL4298771 | 0.98 | CYP1A2 (0.58) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| Bromide SCHEMBL31318389 | 0.96 | S1PR1 (0.55) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL18531651 | 0.96 | CYP1A2 (0.61) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL14539275 | 0.94 | S1PR1 (0.56) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL294038 | 0.94 | S1PR1 (0.56) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL22363289 | 0.94 | S1PR1 (0.56) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043642-A2 | COMPOSITIONS AND METHODS RELATING TO SOLENOPSINS AND THEIR USES IN TREATING NEUROLOGICAL DISORDERS AND ENHANCING PHYSICAL PERFORMANCE | Synapsin Pharmaceuticals, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008720-A2 | COMPOSITIONS AND METHODS RELATING TO SOLENOPSINS AND THEIR USES IN TREATING NEUROLOGICAL DISORDERS AND ENHANCING PHYSICAL PERFORMANCE | SYNAPSIN PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |