Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 14/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427117 | 0.88 | SCN9A (0.38) | HTR2ASLC6A4KCNH2ARRHEB | |
| SCHEMBL4414450 | 0.86 | AR (0.53) | AR | |
| SCHEMBL6905031 | 0.81 | GRIN2B (0.31) | — | |
| SCHEMBL17222147 | 0.81 | HTR2A (0.40) | HTR2ASLC6A4KCNH2ARRHEB | |
| SCHEMBL6907658 | 0.78 | MRGPRX4 (0.33) | — | |
| SCHEMBL4428667 | 0.77 | HTR2A (0.40) | HTR2ASLC6A4KCNH2ARRHEB | |
| SCHEMBL119682 | 0.77 | HTR2A (0.40) | HTR2ASLC6A4KCNH2ARRHEB | |
| SCHEMBL29427853 | 0.77 | HTR2A (0.40) | HTR2ASLC6A4KCNH2ARRHEB | |
| SCHEMBL1278451 | 0.77 | HTR2A (0.40) | HTR2ASLC6A4KCNH2ARRHEB | |
| SCHEMBL28347300 | 0.75 | HTR2A (0.41) | HTR2ASLC6A4KCNH2ARRHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562569-B1 | ANTIFUNGAL MEDICAMENTS COMPRISING ARYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-12-23 | — | — | EP | claimed |