Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333946 | 1.00 | S1PR1 (0.38) | S1PR1AAK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4415194 | 0.95 | S1PR1 (0.41) | S1PR1AAK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4339891 | 0.95 | S1PR1 (0.41) | S1PR1AAK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4340431 | 0.91 | S1PR1 (0.38) | S1PR1AAK1IDO1 | |
| SCHEMBL4340436 | 0.91 | S1PR1 (0.38) | S1PR1AAK1IDO1 | |
| SCHEMBL11949084 | 0.91 | S1PR1 (0.38) | S1PR1AAK1 | |
| SCHEMBL4331691 | 0.88 | S1PR1 (0.36) | S1PR1AAK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4331685 | 0.88 | S1PR1 (0.36) | S1PR1AAK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1563551 | 0.88 | S1PR1 (0.54) | S1PR1AAK1 | |
| SCHEMBL4416683 | 0.88 | S1PR1 (0.36) | S1PR1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058317-B1 | AMINOPHOSPHORIC ACID ESTER DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2013-10-16 | — | — | EP | disclosed |
| US-8232319-B2 | Amino phosphate derivative and S1P receptor modulator having same as an active ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2012-07-31 | — | — | US | disclosed |
| US-20090325907-A1 | AMINO PHOSPHATE DERIVATIVE AND S1P RECEPTOR MODULATOR HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325907-A1 | AMINO PHOSPHATE DERIVATIVE AND S1P RECEPTOR MODULATOR HAVING SAME AS AN ACTIVE INGREDIENT | S1PR1, S1PR2, S1PR5 | S1PR1 1/4885AAK1 427/4885TAS1R3 1468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.