Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 12/20 | 0.52 |
| ▸ | ENTPD2 | Q9Y5L3 | 2/20 | 0.50 |
| ▸ | P2RY6 | Q15077 | 9/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525149 | 0.85 | SLC28A1 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL437017 | 0.85 | SLC28A1 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL6913156 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL22124733 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Ammonia Solution, Strong SCHEMBL28250466 | 0.83 | SLC28A1 (0.60) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL2988773 | 0.82 | SLC28A1 (0.59) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL1285690 | 0.82 | SLC28A1 (0.59) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL14384430 | 0.81 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Phosphoric Acid SCHEMBL27939255 | 0.81 | P2RY14 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL27807627 | 0.81 | SLC28A1 (0.57) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061460-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | Albany Molecular Research, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1620451-A4 | INDUSTRIALLY SCALABLE NUCLEOSIDE SYNTHESIS | NOVARTIS AG (CH) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008019372-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2008-02-14 | — | — | WO | disclosed |
| EP-1745573-A2 | METHODS OF MANUFACTURE OF 2 -DEOXY-&bgr;-L-NUCLEOSIDES | Microbiologica Quimica E Farmaceutica Ltd. (BR) | 2007-01-24 | — | — | EP | disclosed |
| EP-1620451-A2 | INDUSTRIALLY SCALABLE NUCLEOSIDE SYNTHESIS | Idenix (Cayman) Limited (KY) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004096149-A2 | INDUSTRIALLY SCALABLE NUCLEOSIDE SYNTHESIS | IDENIX (CAYMAN) LIMITED (KY) | 2004-11-11 | — | — | WO | disclosed |
| WO-2004084453-A2 | METHODS OF MANUFACTURE OF 2'-DEOXY-β-L-NUCLEOSIDES | MICROBIOLOGICA QUIMICA E FARMACEUTICA LTD. (BR) | 2004-09-30 | — | — | WO | disclosed |