Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032582 | 1.00 | KMT2A (0.81) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL8219230 | 0.88 | KMT2A (0.77) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL31684031 | 0.87 | KMT2A (0.87) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL27596864 | 0.85 | KMT2A (0.84) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL27500250 | 0.84 | KMT2A (0.81) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL4551056 | 0.83 | KMT2A (0.79) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL30150292 | 0.83 | KMT2A (0.79) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL30150274 | 0.83 | KMT2A (0.79) | KMT2AMEN1ALDH1A1LMNAGBA1 | |
| SCHEMBL8260988 | 0.80 | KMT2A (0.74) | KMT2AMEN1ALDH1A1LMNACHRM4 | |
| SCHEMBL12656085 | 0.79 | KMT2A (0.51) | KMT2AMEN1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |