SCHEMBL4420845

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL4421902	0.84	ABL1 (0.38)	GRM5L3MBTL1PDE4BGRM2HSP90AA1
	SCHEMBL13706957	0.80	GRM5 (0.60)	GRM5PDE4BALDH1A1MAPTHSD17B10
	Hydrochloric Acid SCHEMBL4429413	0.79	GRM5 (0.59)	GRM5PDE4BALDH1A1MAPTHSD17B10
	SCHEMBL4422696	0.78	GRM5 (0.46)	GRM5ALDH1A1GAAMAPTHPGD
	SCHEMBL4423540	0.77	GRM5 (0.47)	GRM5L3MBTL1PDE4BGRM2HSP90AA1
	SCHEMBL4421757	0.77	GRM5 (0.46)	GRM5PDE4BALDH1A1MAPTHPGD
	SCHEMBL13707023	0.76	GRM5 (0.53)	GRM5L3MBTL1HSP90AA1ALDH1A1HPGD
	SCHEMBL4433198	0.75	CYP2C19 (0.54)	L3MBTL1ALDH1A1GSK3BMAPTHPGD
	SCHEMBL13706965	0.73	GRM5 (0.49)	GRM5HSP90AA1ALDH1A1HSP90AB1
	SCHEMBL27661690	0.72	GSK3A (0.38)	L3MBTL1PDE4BGRM2HSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.