⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15337447 | 1.00 | — | — | |
| SCHEMBL17476060 | 0.80 | — | — | |
| SCHEMBL9252032 | 0.80 | — | — | |
| SCHEMBL1680254 | 0.79 | — | — | |
| SCHEMBL266223 | 0.78 | — | — | |
| SCHEMBL14909327 | 0.75 | TAAR1 (0.41) | — | |
| SCHEMBL729364 | 0.75 | TAAR1 (0.41) | — | |
| SCHEMBL7413806 | 0.75 | TAAR1 (0.41) | — | |
| SCHEMBL263839 | 0.74 | — | — | |
| SCHEMBL19443129 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113636931-B | Gene coding compound library initial fragment compound and application thereof in synthesis of gene coding compound library | 康龙化成(宁波)科技发展有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-115066423-B | PD-L1 antagonist compounds | 厦门宝太生物科技股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-3687988-B1 | ANTIBACTERIAL COMPOUND AND USES OF SAME | BIOMERIEUX SA (FR) | 2023-05-03 | — | — | EP | disclosed |
| CN-115066423-A | PD-L1 antagonist compounds | 杭州阿诺生物医药科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-113636931-A | Gene coding compound library initial head fragment compound and application thereof in synthesis of gene coding compound library | 康龙化成(宁波)科技发展有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113302175-A | Bicyclic compounds | 维瓦斯治疗公司 | 2021-08-24 | — | — | CN | disclosed |
| WO-2021129584-A1 | PD-L1 ANTAGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2021-07-01 | — | — | WO | disclosed |
| US-10752640-B2 | Compounds active towards bromodomains | NUEVOLUTION A/S (DK) | 2020-08-25 | — | — | US | disclosed |
| EP-3687988-A1 | ANTIBACTERIAL COMPOUND AND USES OF SAME | bioMérieux (FR) | 2020-08-05 | — | — | EP | disclosed |
| US-10201525-B2 | Tetrazole-substituted arylamides as PX2 and PX2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2019-02-12 | — | — | US | disclosed |
| US-20090326220-A1 | Tetrazole-Substituted Arylamides as P2X3 and P2X2/3 Antagonists | DILLON MICHAEL PATRICK | 2009-12-31 | — | — | US | disclosed |
| US-20080242091-A1 | METAL-POLISHING LIQUID AND POLISHING METHOD | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| US-7414068-B2 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2008-08-19 | — | — | US | disclosed |
| US-20070055081-A1 | Processes for production of alpha-aminooxyketones and alpha-hydroxyketones | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-03-08 | — | — | US | disclosed |
| US-20060035948-A1 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2006-02-16 | — | — | US | disclosed |
| US-5326760-A | Aminobutanoic acid compounds having metalloprotease inhibiting properties | GLAXO, INC. (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1994000119-A1 | AMINOBUTANOIC ACID COMPOUNDS HAVING METALLOPROTEASE INHIBITING PROPERTIES | GLAXO INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |