Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfapyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | AURKA | O14965 | 1/20 | 0.68 |
| ▸ | DHFR | P00374 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfapyridine SCHEMBL29438089 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL668918 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL11706483 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL3714634 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL27741790 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL27974729 | 0.97 | SMN1; SMN2 (0.94) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL668917 | 0.97 | SMN1; SMN2 (0.94) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL11778484 | 0.95 | SMN1; SMN2 (0.91) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL28142861 | 0.94 | SMN1; SMN2 (0.88) | SMN1; SMN2KDM4ELMNAAURKADHFR | |
| Sulfapyridine SCHEMBL2243590 | 0.89 | SMN1; SMN2 (0.79) | SMN1; SMN2KDM4ELMNAAURKADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7447 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260117393-A1 | ETCHING AGENT COMPOSITION AND ETCHING METHOD USING THE SAME | KCTECH CO., LTD. (KR) | 2026-04-30 | — | — | US | claimed |
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| CN-120195301-A | Method and system for detecting various antibiotics in water based on artificial intelligence | 广东中加检测技术股份有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-118465149-B | Pretreatment method for improving analysis efficiency of various antibiotics in organic fertilizer | 生态环境部南京环境科学研究所 | 2025-06-13 | — | — | CN | claimed |
| CN-116890109-B | Preparation method of flexible Raman detection substrate and application of flexible Raman detection substrate in rapid detection of drug residues in water | 广东省科学院测试分析研究所(中国广州分析测试中心) | 2025-06-03 | — | — | CN | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| CN-120025007-A | Application of constructed wetland in removal of sulfonamide antibiotics and resistance genes in water body | 海南热带海洋学院 | 2025-05-23 | — | — | CN | claimed |
| CN-120022878-A | Amphiphilic covalent organic framework mixed mode chromatographic stationary phase and preparation method and application thereof | 河南工业大学 | 2025-05-23 | — | — | CN | claimed |
| EP-4552661-A2 | MEDICAL DEVICES HAVING ANTI-MICROBIAL PROPERTIES AND METHODS FOR MAKING THE SAME | Hollister Incorporated (US) | 2025-05-14 | — | — | EP | claimed |
| EP-4178637-B1 | MEDICAL DEVICES HAVING ANTI-MICROBIAL PROPERTIES AND METHODS FOR MAKING THE SAME | HOLLISTER INC (US) | 2025-05-14 | — | — | EP | claimed |
| EP-0572560-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO, Howard, K. (US) | 1993-12-08 | — | — | EP | claimed |
| US-5208150-A | Adding 7-ethyl-2-methyl-4-undecanol hydrogen sulfate and salts to suppress Salmonella | THE UNIVERSITY OF MARYLAND (US) | 1993-05-04 | — | — | US | claimed |
| WO-1992017607-A1 | SALMONELLA-SELECTIVE PLATING MEDIUM | UNIVERSITY OF MARYLAND COLLEGE PARK (US) | 1992-10-15 | — | — | WO | claimed |
| WO-1992014456-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 1992-09-03 | — | — | WO | claimed |
| US-4725355-A | SULFA DRUG ON SUPPORT | TERUMO KABUSHIKI KAISHA (JP) | 1988-02-16 | — | — | US | claimed |
| US-4599416-A | Process for the preparation of aqueous solutions of potentiated sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1986-07-08 | — | — | US | claimed |
| US-4532245-A | Pharmaceutical compositions | HOFFMANN-LA ROCHE INC. (US) | 1985-07-30 | — | — | US | claimed |
| US-4315931-A | MICROBIOCIDES, INFECTIOUS DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4122158-A | FOR TREATMENT OF BURNS; BIODEGRADABLE HYDROPHOBIC POLYMER; SUSTAINED RELEASE | ALZA CORPORATION (US) | 1978-10-24 | — | — | US | claimed |
| US-3983209-A | HYDROPHOBIC BIOERODIBLE POLYMER, MICROBIOCIDE OR PROTEOLYTIC ENZYME | ALZA CORPORATION (US) | 1976-09-28 | — | — | US | claimed |