SCHEMBL4422164

SCHEMBL4422164

C=CCc1ccc2c(c1)OBO2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.58
MAPT P10636 4/20 0.58
CYP1A2 P05177 1/20 0.58
XDH P47989 1/20 0.46
ALDH1A1 P00352 7/20 0.44
GABRA1 P14867 4/20 0.44
GABRB2 P47870 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
GAA P10253 3/20 0.44
CNR2 P34972 3/20 0.44
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CNR1 P21554 2/20 0.44
ALDH2 P05091 1/20 0.44
AKR1B1 P15121 1/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
PPARA Q07869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7698498 0.74 CYP3A4 (0.54) CYP3A4MAPTCYP1A2XDHALDH1A1
SCHEMBL24649587 0.74 CYP3A4 (0.54) CYP3A4MAPTCYP1A2XDHALDH1A1
Safrole SCHEMBL29368306 0.73 CYP3A4 (1.00) CYP3A4MAPTCYP1A2ALDH1A1GAA
SCHEMBL8063264 0.73 MAPT (0.79) CYP3A4MAPTCYP1A2XDHALDH1A1
Safrole SCHEMBL56828 0.73 CYP3A4 (1.00) CYP3A4MAPTCYP1A2ALDH1A1GAA
Safrole SCHEMBL2039562 0.73 CYP3A4 (1.00) CYP3A4MAPTCYP1A2ALDH1A1GAA
Safrole SCHEMBL28606225 0.72 CYP3A4 (0.96) CYP3A4MAPTCYP1A2ALDH1A1GAA
SCHEMBL30367930 0.72 CYP3A4 (0.51) CYP3A4MAPTCYP1A2XDHALDH1A1
SCHEMBL8518550 0.71 CNR1 (0.42) CYP3A4ALDH1A1CNR2CNR1ALOX5
SCHEMBL14482492 0.70 CYP3A4 (0.50) CYP3A4MAPTCYP1A2XDHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009139864-A2 FLUORESCENCE DETECTION OF POISON OAK OIL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-11-19 WO claimed
WO-2009139864-A2 FLUORESCENCE DETECTION OF POISON OAK OIL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-11-19 WO disclosed