Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | GRB2 | P62993 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563524 | 0.99 | STING1 (0.67) | STING1GLAKDM4ELTB4RTDP1 | |
| SCHEMBL4422470 | 0.97 | STING1 (0.65) | STING1GLAKDM4ELTB4RTDP1 | |
| SCHEMBL4422465 | 0.86 | GLA (0.51) | STING1GLAKDM4ELTB4RTTR | |
| SCHEMBL20763371 | 0.84 | STING1 (0.64) | STING1GLAKDM4ELTB4RTDP1 | |
| SCHEMBL20762975 | 0.82 | STING1 (0.62) | STING1GLAKDM4ELTB4RTDP1 | |
| SCHEMBL20762977 | 0.82 | STING1 (0.62) | STING1GLAKDM4ELTB4RTDP1 | |
| SCHEMBL20762921 | 0.81 | STING1 (0.75) | STING1GLAKDM4ELTB4RTDP1 | |
| Vadimezan SCHEMBL4282930 | 0.81 | STING1 (0.97) | STING1GLAKDM4ETDP1 | |
| SCHEMBL20762991 | 0.81 | STING1 (0.79) | STING1GLAKDM4ETDP1 | |
| SCHEMBL20763359 | 0.80 | STING1 (0.73) | STING1GLAKDM4ELTB4RTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156459-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-30 | — | — | WO | claimed |
| WO-2009156459-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-30 | — | — | WO | disclosed |