⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8798245 | 0.95 | — | — | |
| SCHEMBL23283988 | 0.76 | — | — | |
| SCHEMBL14100916 | 0.76 | — | — | |
| SCHEMBL13748244 | 0.73 | — | — | |
| SCHEMBL18664570 | 0.71 | — | — | |
| SCHEMBL15038843 | 0.71 | — | — | |
| SCHEMBL24933643 | 0.71 | — | — | |
| SCHEMBL12936971 | 0.70 | — | — | |
| SCHEMBL763416 | 0.70 | — | — | |
| SCHEMBL19075107 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1583701-A | Environmental protection cleaning process for preparing high-purity ortho-acetate | GU LIHUA (CN) | 2005-02-23 | — | — | CN | claimed |
| US-4456769-A | ONE-STEP REACTION OF AN IMIDOESTER WITH HYDRAZINE HYDRATE | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | claimed |
| EP-3319955-B1 | 6-AMINO-QUINOLINE-3-CARBONITRILS AS COT MODULATORS | GILEAD SCIENCES INC (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3224258-B1 | 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-3-AMINE COMPOUNDS AS CBP AND/OR EP300 INHIBITORS | GENENTECH INC (US) | 2019-08-14 | — | — | EP | disclosed |
| WO-2019010482-A1 | COMPOSITIONS AND METHODS FOR MODULATING CERVICAL RIPENING | CASE WESTERN RESERVE UNIVERSITY (US) | 2019-01-10 | — | — | WO | disclosed |
| US-20180140607-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-2831060-B1 | NOVEL 4-METHYL-DIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2016-05-04 | — | — | EP | disclosed |
| EP-2601189-B1 | N-((6-AMINO-PYRIDIN-3-YL)METHYL)-HETEROARYL-CARBOXAMIDES AS INHIBITORS OF PLASMA KALLIKREIN | NOVARTIS AG (CH) | 2015-04-15 | — | — | EP | disclosed |
| US-8618311-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2013-12-31 | — | — | US | disclosed |
| US-20130090483-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2013-04-11 | — | — | US | disclosed |
| US-8344162-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2013-01-01 | — | — | US | disclosed |
| WO-2011045415-A2 | NEW IMAGING AGENTS AND THEIR USE FOR THE DIAGNOSTIC IN VIVO OF NEURODEGENERATIVE DISEASES, NOTABLY ALZHEIMER'S DISEASE AND DERIVATIVE DISEASES | GUERBET (FR) | 2011-04-21 | — | — | WO | disclosed |
| US-20100217014-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2010-08-26 | — | — | US | disclosed |
| US-7754897-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2010-07-13 | — | — | US | disclosed |
| EP-1915340-A2 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | Cardiome Pharma Corp. (CA) | 2008-04-30 | — | — | EP | disclosed |
| US-20070015924-A1 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2007-01-18 | — | — | US | disclosed |
| WO-2006138673-A2 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2006-12-28 | — | — | WO | disclosed |
| EP-0165628-B1 | CYCLOALKANE-INDENE-CARBOXIMIDAMIDE DERIVATIVES | AKZO N.V. (NL) | 1988-09-21 | — | — | EP | disclosed |
| US-4661522-A | Cycloalkane-indene-carboximidamide derivatives | AKZO N.V. (NL) | 1987-04-28 | — | — | US | disclosed |
| EP-0165628-A1 | Cycloalkane-indene-carboximidamide derivatives | AKZO N.V. (NL) | 1985-12-27 | — | — | EP | disclosed |