Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 19/20 | 0.71 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.71 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423203 | 1.00 | MAP3K14 (0.71) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL4434183 | 1.00 | MAP3K14 (0.71) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL12714812 | 1.00 | MAP3K14 (0.71) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL4434180 | 1.00 | MAP3K14 (0.71) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL4432586 | 1.00 | MAP3K14 (0.71) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL1614105 | 0.96 | MAP3K14 (0.75) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL12714766 | 0.94 | MAP3K14 (0.73) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL1614356 | 0.94 | MAP3K14 (0.73) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL1613134 | 0.94 | MAP3K14 (0.73) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL1614449 | 0.94 | MAP3K14 (0.73) | MAP3K14MAP4K4PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158011-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2009-12-30 | — | — | WO | disclosed |