SCHEMBL4423857

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4419839	0.89	EGFR (1.00)	EGFRERBB2LCKKDRPRKD3
	SCHEMBL6098604	0.86	EGFR (0.79)	EGFRERBB2LCKKDRPRKD3
	SCHEMBL3555278	0.84	EGFR (0.76)	EGFRERBB2LCKKDRPRKD3
	SCHEMBL1220077	0.83	EGFR (1.00)	EGFRERBB2LCKKDRPRKD3
	SCHEMBL1219502	0.81	EGFR (0.76)	EGFRERBB2LCKKDRAAK1
	SCHEMBL6101136	0.80	EGFR (0.84)	EGFRERBB2LCKKDRPRKD3
	SCHEMBL1219572	0.79	EGFR (0.83)	EGFRERBB2LCKKDRAAK1
	SCHEMBL2443464	0.79	EGFR (1.00)	EGFRERBB2LCKKDRPRKD3
	SCHEMBL4551995	0.79	EGFR (0.94)	EGFRERBB2
	SCHEMBL3555249	0.78	EGFR (0.77)	EGFRERBB2LCKKDRPRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.