Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434067 | 0.93 | CCR3 (0.46) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4433571 | 0.92 | CCR3 (0.45) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4433523 | 0.92 | CCR3 (0.45) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4428305 | 0.92 | CCR3 (0.45) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4429017 | 0.91 | CCR3 (0.44) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4434042 | 0.84 | CCR3 (0.47) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4421298 | 0.84 | CCR3 (0.46) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14369031 | 0.84 | CCR3 (0.43) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14369062 | 0.81 | CCR3 (0.54) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL5662634 | 0.79 | CCR3 (0.40) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024359-A1 | COMPOUNDS THAT ARE AGONISTS OF MUSCARINIC RECEPTORS AND THAT MAY BE EFFECTIVE IN TREATING PAIN, ALZHEIMER'S DECEASE AND/OR SCHIZOPHRENIA | AstraZeneca AB (SE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007126362-A1 | COMPOUNDS THAT ARE AGONISTS OF MUSCARINIC RECEPTORS AND THAT MAY BE EFFECTIVE IN TREATING PAIN, ALZHEIMER'S DISEASE AND/OR SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | WO | disclosed |