SCHEMBL4425340

SCHEMBL4425340

OCCCCCCCCCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.64
ALDH1A1 P00352 7/20 0.44
HPGD P15428 6/20 0.44
HSD17B10 Q99714 5/20 0.44
TSHR P16473 3/20 0.44
CYP3A4 P08684 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 5/20 0.42
POLB P06746 2/20 0.40
HTT P42858 1/20 0.40
GBA1 P04062 2/20 0.39
UGCG Q16739 2/20 0.39
GBA2 Q9HCG7 2/20 0.39
CYP1A2 P05177 4/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979416 1.00 KMT2A (0.64) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL15511217 1.00 KMT2A (0.64) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL10770344 1.00 KMT2A (0.64) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL9815036 1.00 KMT2A (0.64) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL2560886 1.00 KMT2A (0.64) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL29364503 0.98 KMT2A (0.66) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL506054 0.98 KMT2A (0.66) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL500630 0.93 KMT2A (0.68) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL6412633 0.91 KMT2A (0.69) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL27523973 0.88 MEN1 (0.50) KMT2AMEN1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660638-B1 LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME INTEGRAL MOLECULAR INC (US) 2015-12-23 EP disclosed
US-9213027-B2 Lipoparticles comprising proteins, methods of making, and using the same INTEGRAL MOLECULAR, INC. (US) 2015-12-15 US disclosed
US-20140135230-A1 Lipoparticles Comprising Proteins, Methods Of Making, And Using The Same INTEGRAL MOLECULAR, INC. (US) 2014-05-15 US disclosed
US-8574590-B2 Lipoparticles comprising proteins, methods of making, and using the same INTEGRAL MOLECULAR, INC. (US) 2013-11-05 US disclosed
EP-1660638-A4 LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME INTEGRAL MOLECULAR INC (US) 2009-02-18 EP disclosed
EP-1758447-A4 COLOR-CHANGING FISHING EQUIPMENT PURE FISHING INC (US) 2008-06-04 EP disclosed
EP-1758447-A2 COLOR-CHANGING FISHING EQUIPMENT Pure Fishing, Inc. (US) 2007-03-07 EP disclosed
EP-1660638-A2 LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME Integral Molecular, Inc. (US) 2006-05-31 EP disclosed
WO-2006009606-A2 COLOR-CHANGING FISHING EQUIPMENT PURE FISHING, INC. (US) 2006-01-26 WO disclosed
US-20050274055-A1 Color-changing fishing equipment PURE FISHING, INC. 2005-12-15 US disclosed
EP-0884324-A2 Method for generating an anilinothiozolinone by treatment of a phenylthiocarbamyl amino acid with a Lewis acid in protein sequencing Beckman Coulter, Inc. (US) 1998-12-16 EP disclosed
US-5837202-A METAL CHELATES AS DETECTORS FOR FLUORESCENCE WITH LIPIDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-11-17 US disclosed
EP-0590145-B1 FIBER OPTIC SENSOR AND METHODS FOR DETECTING AN ORGANIC ANALYTE IN A FLUID OR VAPOR SAMPLE TUFTS COLLEGE (US) 1998-09-02 EP disclosed
US-5616790-A FLUORESCENT CHELATE COMPOUND AS METAL ION DETECTOR CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1997-04-01 US disclosed
WO-1996016327-A1 FLUORESCENT METAL-CHELATING AMPHIPHILE AND SENSOR CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1996-05-30 WO disclosed
US-5512490-A SUPPORT, ARRAY OF HETEROGENEOUS SEMISELECTIVE THIN FILMS WHICH FUNCTION AS SENSING RECEPTOR UNITS TRUSTEES OF TUFTS COLLEGE (US) 1996-04-30 US disclosed
US-5270213-A Protein sequencing PORTON INSTRUMENTS, INC. (US) 1993-12-14 US disclosed
US-5244813-A Fiber optic sensor, apparatus, and methods for detecting an organic analyte in a fluid or vapor sample TRUSTEES OF TUFTS COLLEGE (US) 1993-09-14 US disclosed
EP-0549752-A1 PROTEIN SEQUENCING BECKMAN INSTRUMENTS, INC. (US) 1993-07-07 EP disclosed
WO-1993000355-A1 PROTEIN SEQUENCING PORTON INSTRUMENTS, INC. (US) 1993-01-07 WO disclosed