Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1206563 | 0.92 | CA1 (0.41) | TDP1CA1CA2MEN1POLB | |
| Acetic Acid SCHEMBL131569 | 0.86 | FFAR3 (0.39) | TDP1CA1CA2MEN1POLB | |
| Acetic Acid SCHEMBL27627871 | 0.86 | FFAR3 (0.39) | TDP1CA1CA2MEN1POLB | |
| Propene SCHEMBL23361925 | 0.86 | MEN1 (0.44) | TDP1CA1CA2MEN1POLB | |
| Propene SCHEMBL314173 | 0.86 | MEN1 (0.44) | TDP1CA1CA2MEN1POLB | |
| Propene SCHEMBL29001622 | 0.86 | MEN1 (0.44) | TDP1CA1CA2MEN1POLB | |
| Bicarbonate SCHEMBL10456880 | 0.84 | CA1 (0.37) | TDP1CA1CA2MEN1POLB | |
| Acetic Acid SCHEMBL667791 | 0.84 | TDP1 (0.37) | TDP1CA1CA2MEN1POLB | |
| Acetic Acid SCHEMBL8953871 | 0.84 | TDP1 (0.37) | TDP1CA1CA2MEN1POLB | |
| Oxalic Acid SCHEMBL28528613 | 0.83 | CA1 (0.39) | TDP1CA1CA2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104371508-A | Weather-resistant coating composite film | SUZHOU FIRST NEW MATERIAL CO LTD | 2015-02-25 | — | — | CN | claimed |
| EP-0850932-B1 | Salts of heterocyclic anions and their uses as ionic conductive materials | CENTRE NAT RECH SCIENT (FR) | 2009-07-22 | — | — | EP | claimed |
| CN-104371508-A | Weather-resistant coating composite film | SUZHOU FIRST NEW MATERIAL CO LTD | 2015-02-25 | — | — | CN | disclosed |