SCHEMBL4425643

SCHEMBL4425643

CCc1c(C(=O)O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 13/20 0.61
CNR2 P34972 10/20 0.61
HTR2A P28223 3/20 0.53
HTR2C P28335 3/20 0.53
SLC6A4 P31645 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL738485 0.87 CNR1 (0.68) CNR1CNR2HTR2AHTR2C
SCHEMBL6102985 0.83 CNR1 (0.67) CNR1CNR2
SCHEMBL3683934 0.83 CNR1 (0.89) CNR1CNR2
SCHEMBL6106568 0.82 CNR1 (0.68) CNR1CNR2
SCHEMBL4914879 0.81 CNR1 (0.61) CNR1CNR2
SCHEMBL24238305 0.80 CNR1 (0.60) CNR1CNR2
SCHEMBL30961580 0.80 CNR1 (0.60) CNR1CNR2
SCHEMBL4923037 0.79 CNR1 (0.57) CNR1CNR2
SCHEMBL3680322 0.79 CNR1 (0.71) CNR1CNR2
SCHEMBL4065973 0.78 CNR1 (0.69) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2026798-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS Solvay Pharmaceuticals GmbH (DE) 2009-02-25 EP disclosed
WO-2007125048-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-08 WO disclosed