Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 17/20 | 0.73 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605406 | 0.86 | HRH4 (0.71) | HRH4DRD3HRH3PRKAB2PRKAG1 | |
| SCHEMBL4421411 | 0.86 | HRH4 (0.70) | HRH4DRD3HRH3PRKAB2PRKAG1 | |
| SCHEMBL605118 | 0.84 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL603386 | 0.83 | HRH4 (0.83) | HRH4HRH3 | |
| SCHEMBL605157 | 0.83 | HRH4 (1.00) | HRH4DRD3HRH3PRKAB2PRKAG1 | |
| SCHEMBL602184 | 0.83 | HRH4 (0.80) | HRH4DRD3HRH3 | |
| SCHEMBL13341051 | 0.82 | HRH4 (0.82) | HRH4DRD3 | |
| SCHEMBL606394 | 0.81 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL603489 | 0.81 | HRH4 (1.00) | HRH4DRD3HRH3 | |
| SCHEMBL2164915 | 0.81 | HRH4 (0.86) | HRH4DRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673348-B1 | BENZOIMIDAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-01 | — | — | EP | claimed |