⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441644 | 0.67 | — | — | |
| SCHEMBL11463029 | 0.67 | — | — | |
| SCHEMBL1472 | 0.64 | — | — | |
| SCHEMBL9070434 | 0.61 | — | — | |
| SCHEMBL21603104 | 0.61 | — | — | |
| SCHEMBL667876 | 0.61 | — | — | |
| SCHEMBL169060 | 0.61 | — | — | |
| SCHEMBL9830566 | 0.58 | — | — | |
| SCHEMBL9832369 | 0.58 | — | — | |
| SCHEMBL246315 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174577-A1 | PHTHALAZINE ISOXAZOLE ALKOXY DERIVATIVES, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2019-09-19 | — | — | WO | claimed |
| CN-105295607-B | A kind of aqueous wooden ware seal coat and preparation method thereof | 万华化学集团股份有限公司 | 2017-09-19 | — | — | CN | disclosed |
| CN-102834387-A | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | BAYER CROPSCIENCE AG | 2012-12-19 | — | — | CN | disclosed |
| CN-101171113-B | Method for producing a coated sheet, resulting sheet, and use thereof for producing molded parts, in particular for use in automobile construction | BASF COATINGS AG | 2010-12-01 | — | — | CN | disclosed |
| WO-2009142535-A1 | DICYCLOPENTADIENE METATHESIS POLYMERISATION CATALYST | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ОБЪЕДИНЁННЫЙ ЦЕНТР ИССЛЕДОВАНИЙ И РАЗРАБОТОК" (RU) | 2009-11-26 | — | — | WO | disclosed |
| CN-101445505-A | Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes | ASTRAZENECA AB (SE) | 2009-06-03 | — | — | CN | disclosed |
| CN-101445502-A | Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes | ASTRAZENECA AB (SE) | 2009-06-03 | — | — | CN | disclosed |
| CN-101386618-A | Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes | ASTRAZENECA AB (SE) | 2009-03-18 | — | — | CN | disclosed |
| CN-101263140-A | Heterobicyclic compounds as glucokinase activators | ASTRAZENECA AB (SE) | 2008-09-10 | — | — | CN | disclosed |
| CN-101258150-A | Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes | ASTRAZENECA AB (SE) | 2008-09-03 | — | — | CN | disclosed |
| CN-101182378-A | Nanoparticle Modified Polyisocyanates | BAYER MATERIALSCIENCE AG (DE) | 2008-05-21 | — | — | CN | disclosed |
| CN-101171113-A | Method for producing a coated sheet, resulting sheet, and use thereof for producing molded parts, in particular for use in automobile construction | BASF COATINGS AG (DE) | 2008-04-30 | — | — | CN | disclosed |