Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.70 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.70 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.70 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.70 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.70 |
| ▸ | NAAA | Q02083 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863086 | 1.00 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL13709041 | 1.00 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL8366892 | 1.00 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL3869201 | 1.00 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL4326160 | 0.98 | HDAC1 (0.68) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL5969581 | 0.98 | HDAC1 (0.68) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5855204 | 0.98 | HDAC1 (0.67) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL1467538 | 0.93 | NPC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL15065078 | 0.92 | GRIN1 (0.61) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL19874469 | 0.91 | NPC1 (0.64) | HDAC1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284469-B1 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | GENZYME CORP (US) | 2020-11-04 | — | — | EP | disclosed |
| EP-3284469-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | Genzyme Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2535050-B1 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORP (US) | 2017-07-05 | — | — | EP | disclosed |
| US-8431335-B2 | Glucosyl ceramide, sodium taurocholate, and buffer; bioassays | GENZYME CORPORATION (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431335-B2 | Glucosyl ceramide, sodium taurocholate, and buffer; bioassays | GENZYME CORPORATION (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431335-B2 | Glucosyl ceramide, sodium taurocholate, and buffer; bioassays | GENZYME CORPORATION (US) | 2013-04-30 | — | — | US | disclosed |
| EP-2535050-A2 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2061477-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | Genzyme Corporation (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080248513-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080248512-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080248512-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080248512-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080248513-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080248513-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080145836-A1 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080145836-A1 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080145836-A1 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-06-19 | — | — | US | disclosed |
| WO-2008033427-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | GENZYME CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |