SCHEMBL4426404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4431399	0.92	HDAC1 (0.63)	HDAC1KCNH2HDAC3HDAC4HDAC7
	SCHEMBL4420253	0.84	ACKR3 (0.67)	HDAC1HPGDSACKR3
	SCHEMBL8288741	0.81	HDAC1 (0.70)	HDAC1KCNH2HDAC3HDAC4HDAC7
	SCHEMBL4419037	0.78	HDAC1 (0.56)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL1891586	0.77	ACKR3 (0.68)	HDAC1HPGDSACKR3NPC1RAB9A
	SCHEMBL21616358	0.77	HDAC1 (0.59)	HDAC1KCNH2HDAC3HDAC4HDAC7
	SCHEMBL4430258	0.76	ACKR3 (0.70)	HDAC1ACKR3
	SCHEMBL1885544	0.76	HDAC1 (0.67)	HDAC1HPGDSACKR3NPC1RAB9A
	SCHEMBL6518279	0.76	HDAC1 (0.60)	HDAC1KCNH2HDAC3HDAC4HDAC7
	SCHEMBL8289901	0.74	HDAC1 (0.76)	HDAC1KCNH2HDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.