Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 15/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863830 | 0.96 | CREBBP (0.60) | CREBBPTRPV1PLAUPLATOGG1 | |
| SCHEMBL4429044 | 0.92 | CREBBP (0.60) | CREBBPTRPV1 | |
| SCHEMBL4426859 | 0.90 | CREBBP (0.62) | CREBBPTRPV1 | |
| SCHEMBL4434512 | 0.86 | CREBBP (0.73) | CREBBPTRPV1 | |
| SCHEMBL13865652 | 0.85 | CREBBP (0.60) | CREBBPTRPV1 | |
| SCHEMBL4427826 | 0.83 | CREBBP (0.64) | CREBBPTRPV1 | |
| SCHEMBL4422899 | 0.82 | CREBBP (0.67) | CREBBPTRPV1 | |
| SCHEMBL4424245 | 0.82 | CREBBP (0.61) | CREBBPTRPV1 | |
| SCHEMBL13998316 | 0.81 | TRPV1 (0.64) | CREBBPTRPV1 | |
| SCHEMBL4428957 | 0.81 | CREBBP (0.58) | CREBBPTRPV1OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033953-A1 | Vanilloid receptor modulators | Glaxo Group Limited (GB) | 2009-03-11 | — | — | EP | disclosed |