Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 20/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381324 | 0.92 | P2RY1 (0.54) | P2RY1P2RY14P2RY2KCNH2 | |
| SCHEMBL4424711 | 0.89 | P2RY1 (0.55) | P2RY1P2RY14P2RY2KCNH2 | |
| SCHEMBL4424620 | 0.87 | P2RY1 (0.52) | P2RY1P2RY14P2RY2KCNH2 | |
| SCHEMBL1380998 | 0.87 | P2RY1 (0.54) | P2RY1P2RY14P2RY2KCNH2 | |
| SCHEMBL4552189 | 0.86 | P2RY1 (0.48) | P2RY1P2RY14P2RY2KCNH2 | |
| SCHEMBL4423173 | 0.85 | P2RY1 (0.51) | P2RY1P2RY14P2RY2KCNH2 | |
| SCHEMBL4422591 | 0.81 | P2RY1 (0.57) | P2RY1P2RY14P2RY2 | |
| SCHEMBL4425574 | 0.79 | P2RY1 (0.55) | P2RY1P2RY14P2RY2 | |
| SCHEMBL4423200 | 0.79 | P2RY1 (0.53) | P2RY1P2RY14P2RY2 | |
| SCHEMBL4423719 | 0.79 | P2RY1 (0.56) | P2RY1P2RY14P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750704-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2009-07-22 | — | — | EP | claimed |