SCHEMBL4428119

SCHEMBL4428119

C=CCCCC(=CCC)CCCC=CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
USP2 O75604 1/20 0.32
CYP3A4 P08684 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
F7 P08709 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CYP19A1 P11511 1/20 0.32
F3 P13726 1/20 0.32
RXRA P19793 1/20 0.32
PTGS1 P23219 1/20 0.32
PPARG P37231 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
OXER1 Q8TDS5 1/20 0.32
ABCC4 O15439 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11304782 0.86 TSHR (0.44) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL29284328 0.84 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL4739279 0.84 TSHR (0.41) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL3242777 0.83 MAPT (0.42) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL10729128 0.82 TSHR (0.50) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL847257 0.82 TSHR (0.42) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL11416904 0.82 TSHR (0.50) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL7185411 0.82 TSHR (0.50) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL847258 0.82 TSHR (0.42) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL27321436 0.81 TSHR (0.56) TSHRALDH1A1LMNAMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2092004-A1 FILLED POLYOLEFIN COMPOSITIONS Basell Poliolefine Italia S.r.l. (IT) 2009-08-26 EP disclosed
EP-2092015-A1 FILLED POLYOLEFIN COMPOSITIONS Basell Poliolefine Italia S.r.l. (IT) 2009-08-26 EP disclosed
WO-2008074715-A1 FILLED POLYOLEFIN COMPOSITIONS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2008-06-26 WO disclosed
WO-2008074713-A1 FILLED POLYOLEFIN COMPOSITIONS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2008-06-26 WO disclosed
EP-1765884-A1 POLYMERIZATION PROCESS ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2007-03-28 EP disclosed
WO-2006009977-A1 POLYMERIZATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-01-26 WO disclosed