Guanidine

Guanidine

SCHEMBL4428313

CNC(=N)N.N=C(N)N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181641 0.96
Hydrochloric Acid SCHEMBL27469418 0.92
Bromide SCHEMBL11505134 0.92
Hydrochloric Acid SCHEMBL439854 0.92
Methane SCHEMBL28838006 0.92
Ethane SCHEMBL27569889 0.92
SCHEMBL29183240 0.92
Water SCHEMBL1971738 0.92
SCHEMBL28868195 0.92
Iodide SCHEMBL9536874 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1030894-B2 CONDUCTIVE ORGANIC COATINGS HENKEL AG & CO KGAA (DE) 2009-10-28 EP claimed
EP-1030894-B1 CONDUCTIVE ORGANIC COATINGS HENKEL KGAA (DE) 2003-07-02 EP claimed
EP-1030894-A1 CONDUCTIVE ORGANIC COATINGS Henkel Kommanditgesellschaft auf Aktien (DE) 2000-08-30 EP claimed
WO-1999024515-A1 CONDUCTIVE ORGANIC COATINGS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-05-20 WO claimed
CN-107250130-B Heterocyclic compound and pharmaceutical composition comprising it BEYONDBIO株式会社 2019-11-08 CN disclosed
CN-107250130-A Heterocyclic compound and the pharmaceutical composition comprising it BEYONDBIO株式会社 2017-10-13 CN disclosed
EP-1590338-A2 MODULATORS OF MELANOCORTIN RECEPTOR Gene Logic Inc. (US) 2005-11-02 EP disclosed
WO-2004050610-A2 MODULATORS OF MELANOCORTIN RECEPTOR GENE LOGIC INC. (US) 2004-06-17 WO disclosed