Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141804 | 0.91 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3221024 | 0.90 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL3225945 | 0.86 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3228092 | 0.85 | KCNH2 (0.54) | KCNH2SLC2A1 | |
| SCHEMBL2937576 | 0.84 | KCNH2 (0.79) | KCNH2SLC2A1 | |
| SCHEMBL3144363 | 0.79 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| SCHEMBL3227007 | 0.78 | KCNH2 (0.45) | KCNH2SLC2A1 | |
| Gsk-945237 SCHEMBL3141752 | 0.78 | KCNH2 (0.79) | KCNH2SLC2A1 | |
| Gsk-945237 SCHEMBL30480761 | 0.78 | KCNH2 (0.79) | KCNH2SLC2A1 | |
| SCHEMBL3139217 | 0.78 | KCNH2 (0.56) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136807-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | Glaxo Group Limited (GB) | 2009-12-30 | — | — | EP | claimed |
| WO-2008125594-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | WO | claimed |
| EP-2136807-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | Glaxo Group Limited (GB) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008125594-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | WO | disclosed |