Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136709 | 1.00 | FABP5 (0.40) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL8494693 | 0.90 | FABP5 (0.41) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL2544051 | 0.87 | FABP5 (0.41) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL29875636 | 0.87 | KMT2A (0.40) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL21581904 | 0.87 | KMT2A (0.40) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL30112800 | 0.87 | KMT2A (0.40) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL28863858 | 0.87 | KMT2A (0.44) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL29722201 | 0.87 | MDM4 (0.39) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL28863857 | 0.87 | KMT2A (0.44) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL29397011 | 0.87 | KMT2A (0.40) | FABP5FABP7KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632996-B2 | Method for producing recombinant antibody and antibody fragment thereof | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |
| EP-1085090-B1 | IgA NEPHROPATHY-ASSOCIATED DNA | UNIV NIHON (JP) | 2011-12-14 | — | — | EP | disclosed |
| EP-2077275-A2 | IgA nephropathy-related DNA | Nihon University (JP) | 2009-07-08 | — | — | EP | disclosed |
| EP-1992644-A1 | Antibodies against CCR4 and its fragments | Kyowa Hakko Kogyo Co., Ltd (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1975175-A2 | IgA nephropathy-related DNA | Nihon University (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-1270595-B1 | ANTI CCR4 ANTIBODY AND ITS FRAGMENT | KYOWA HAKKO KOGYO KK (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1939286-A1 | NOVEL PEPTIDES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
| US-7332301-B2 | Insulin-like growth factor binding protein | KYOWA HAAKKO KOGYO CO. LTD. (JP) | 2008-02-19 | — | — | US | disclosed |
| US-20060216739-A1 | Insulin-like growth factor binding protein | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-7071160-B2 | Insulin-like growth factor-binding protein | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-0922710-A1 | PEPTIDES PROMOTING THE ACTIVATION OF LATENT TGF-$g(b) AND METHOD FOR SCREENING TGF-$g(b) ACTIVITY REGULATORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0672679-B1 | PHOSPHOLIPASE C INHIBITING PEPTIDE | KYOWA HAKKO KOGYO KK (JP) | 1998-01-28 | — | — | EP | disclosed |
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5532359-A | FUNGICIDES | GENENTECH, INC. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0679658-A1 | ENDOTHELIN-ANTAGONIZING PEPTIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0672679-A1 | PHOSPHOLIPASE C INHIBITING PEPTIDE | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1995-09-20 | — | — | EP | disclosed |
| EP-0672680-A1 | NOVEL PEPTIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |