Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429465 | 0.88 | C3AR1 (0.50) | C3AR1 | |
| SCHEMBL4989549 | 0.82 | C3AR1 (0.44) | C3AR1 | |
| SCHEMBL4989542 | 0.82 | C3AR1 (0.44) | C3AR1 | |
| SCHEMBL4988947 | 0.82 | FOLH1 (0.44) | C3AR1 | |
| SCHEMBL14090802 | 0.81 | C3AR1 (0.40) | C3AR1 | |
| SCHEMBL4430852 | 0.81 | C3AR1 (0.46) | C3AR1 | |
| SCHEMBL4989708 | 0.81 | C3AR1 (0.41) | C3AR1 | |
| SCHEMBL4990143 | 0.80 | C3AR1 (0.42) | C3AR1 | |
| SCHEMBL14091004 | 0.80 | C3AR1 (0.47) | C3AR1 | |
| SCHEMBL4553830 | 0.80 | C3AR1 (0.41) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |