Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.34 |
| ▸ | ACHE | P22303 | 8/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2982765 | 0.89 | PTGS1 (0.32) | BCHEACHEAOC3NPY5R | |
| SCHEMBL2982768 | 0.89 | PTGS1 (0.32) | BCHEACHEAOC3NPY5R | |
| SCHEMBL4433892 | 0.89 | AOC3 (0.34) | BCHEACHEAOC3MTNR1AMTNR1B | |
| SCHEMBL2988795 | 0.88 | AOC3 (0.34) | BCHEACHEAOC3 | |
| SCHEMBL2988799 | 0.88 | AOC3 (0.34) | BCHEACHEAOC3 | |
| SCHEMBL2981278 | 0.87 | BCHE (0.34) | BCHEACHEAOC3 | |
| SCHEMBL2981276 | 0.87 | BCHE (0.34) | BCHEACHEAOC3 | |
| SCHEMBL2982797 | 0.86 | AOC3 (0.33) | AOC3 | |
| SCHEMBL2982795 | 0.86 | AOC3 (0.33) | AOC3 | |
| SCHEMBL2978775 | 0.86 | BCHE (0.33) | BCHEACHEAOC3NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |