⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429853 | 0.78 | — | — | |
| SCHEMBL1820701 | 0.72 | — | — | |
| SCHEMBL5713876 | 0.68 | — | — | |
| SCHEMBL5263785 | 0.68 | — | — | |
| SCHEMBL1505652 | 0.68 | — | — | |
| SCHEMBL9600944 | 0.67 | — | — | |
| SCHEMBL1134345 | 0.65 | — | — | |
| SCHEMBL4598497 | 0.65 | — | — | |
| SCHEMBL2189714 | 0.64 | — | — | |
| SCHEMBL4428717 | 0.63 | CYP1A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121672-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-1996546-A2 | SUBSTITUTED GAMMA LACTAMS AS PROSTAGLANDIN EP2 AGONISTS | Allergan, Inc. (US) | 2008-12-03 | — | — | EP | disclosed |
| WO-2008094912-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| EP-1877050-A1 | SUBSTITUTED BETA-LACTAMS AND THEIR USE IN MEDICINE | Allergan, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1856042-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2007109578-A2 | SUBSTITUTED GAMMA LACTAMS AS PROSTAGLANDIN EP2 AGONISTS | ALLERGAN, INC. (US) | 2007-09-27 | — | — | WO | disclosed |
| WO-2006121708-A1 | SUBSTITUTED BETA-LACTAMS AND THEIR USE IN MEDICINE | ALLERGAN, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006098918-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2006-09-21 | — | — | WO | disclosed |