Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223423 | 0.90 | PTGER1 (0.50) | PTGER1 | |
| SCHEMBL3222982 | 0.86 | PTGER1 (0.54) | PTGER1 | |
| SCHEMBL4432069 | 0.86 | PTGER1 (0.55) | PTGER1 | |
| Hydrochloric Acid SCHEMBL3210716 | 0.86 | PTGER1 (0.54) | PTGER1 | |
| SCHEMBL3203442 | 0.84 | PTGER1 (0.59) | PTGER1 | |
| SCHEMBL3200043 | 0.81 | PTGER1 (0.54) | PTGER1 | |
| SCHEMBL3214223 | 0.78 | PTGER1 (0.72) | PTGER1 | |
| SCHEMBL3215497 | 0.77 | PTGER1 (0.56) | PTGER1 | |
| SCHEMBL3213365 | 0.77 | PTGER1 (0.74) | PTGER1 | |
| SCHEMBL3221088 | 0.76 | PTGER1 (0.70) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129670-A2 | BENZOFURAN COMPOUNDS USEFUL IN THE TREATMENT OF CONDITIONS MEDIATED BY THE ACTION OF PGE2 AT THE EP1 RECEPTOR | Glaxo Group Limited (GB) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008098978-A2 | BENZOFURAN COMPOUNDS USEFUL IN THE TREATMENT OF CONDITIONS MEDIATED BY THE ACTION OF PGE2 AT THE EP1 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |