Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | VHL | P40337 | 4/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430311 | 1.00 | ATM (0.51) | ATMVHLPRSS1TPSAB1ECE1 | |
| SCHEMBL4432439 | 0.89 | ATM (0.54) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4432443 | 0.89 | ATM (0.54) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4432404 | 0.88 | ATM (0.50) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4432403 | 0.88 | ATM (0.50) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4434711 | 0.85 | ATM (0.55) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4434719 | 0.85 | ATM (0.55) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4439286 | 0.84 | ATM (0.54) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4439283 | 0.84 | ATM (0.54) | ATMVHLPRSS1TPSAB1MMP2 | |
| SCHEMBL4440608 | 0.83 | ATM (0.50) | ATMVHLPRSS1TPSAB1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |