Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140777 | 0.85 | POLB (0.47) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL1140447 | 0.84 | POLB (0.50) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL1883191 | 0.83 | POLB (0.53) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL1140532 | 0.82 | P2RY12 (0.54) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL596737 | 0.80 | POLB (0.56) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL888227 | 0.80 | POLB (0.42) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL8174805 | 0.79 | POLB (0.59) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL8167619 | 0.79 | POLB (0.59) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL8175190 | 0.78 | POLB (0.60) | POLBP2RX3P2RX2P2RX1RNASEL | |
| SCHEMBL2057095 | 0.77 | POLB (0.55) | POLBP2RX3P2RX2P2RX1RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125856-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008070749-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2008-06-12 | — | — | WO | disclosed |