Vinclozolin

Vinclozolin

SCHEMBL4431315

C=CC1(C)OC(=O)N(c2cc(Cl)cc(Cl)c2)C1=O.c1ccncc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.37
ITGAL P20701 5/20 0.34
ITGB2 P05107 4/20 0.34
ICAM1 P05362 4/20 0.34
AR P10275 1/20 0.33
ITGA4 P13612 1/20 0.32
ITGB7 P26010 1/20 0.32
ELANE P08246 1/20 0.30
CTSG P08311 1/20 0.30
PRTN3 P24158 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vinclozolin SCHEMBL3862172 0.89 TSHR (0.46) TSHRALDH1A1ITGALITGB2ICAM1
Vinclozolin SCHEMBL1517466 0.89 TSHR (0.46) TSHRALDH1A1ITGALITGB2ICAM1
Vinclozolin SCHEMBL21851 0.89 TSHR (0.46) TSHRALDH1A1ITGALITGB2ICAM1
Vinclozolin SCHEMBL15201602 0.79 ITGB2 (0.34) TSHRALDH1A1ITGALITGB2ICAM1
Vinclozolin SCHEMBL8953723 0.77 TSHR (0.36) TSHRALDH1A1ITGALITGB2ICAM1
Vinclozolin SCHEMBL7669329 0.75 TSHR (0.34) TSHRALDH1A1AR
SCHEMBL11839893 0.74 TSHR (0.45) TSHRALDH1A1ITGALITGB2ICAM1
SCHEMBL11839897 0.74 TSHR (0.45) TSHRALDH1A1ITGALITGB2ICAM1
SCHEMBL9246310 0.72 TSHR (0.49) TSHRALDH1A1ITGALITGB2ICAM1
SCHEMBL158206 0.71 AR (0.55) TSHRALDH1A1ITGALITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799776-A4 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE INC (US) 2009-05-06 EP disclosed
EP-1799776-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS Osmose, Inc. (US) 2007-06-27 EP disclosed
WO-2006044218-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE, INC. (US) 2006-04-27 WO disclosed