SCHEMBL4433014

SCHEMBL4433014

C=CCc1nc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6022588 0.73
SCHEMBL3117827 0.72
SCHEMBL7806840 0.71
SCHEMBL16673433 0.71
Hydrochloric Acid SCHEMBL22094064 0.70
SCHEMBL11221112 0.69 CDK1 (0.31)
SCHEMBL1098040 0.68
SCHEMBL7810333 0.67
SCHEMBL2010079 0.67
SCHEMBL175905 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10287220-B2 Fluorination method OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2019-05-14 US claimed
US-6576628-B1 Matrix metalloprotease inhibitors; arthritis, corneal ulcers, arteriosclerosis ROCHE DIAGNOSTICS GMBH (DE) 2003-06-10 US claimed
US-5854062-A Catalyzed enantiomeric selection of 1,2-diols and their cyclization to produce oxiranes ZENECA LIMITED (GB) 1998-12-29 US claimed
EP-0695362-A1 CHIRAL SYNTHESIS OF TERTIARY ALCOHOLS WITH A HYDROLASE ZENECA LIMITED (GB) 1996-02-07 EP claimed
WO-1994024305-A1 CHIRAL SYNTHESIS OF TERTIARY ALCOHOLS WITH A HYDROLASE ZENECA LIMITED (GB) 1994-10-27 WO claimed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US claimed
JP-60042370-A None JP disclosed
CN-108530662-A Decoration is the formed products of metallic 三菱制纸株式会社 2018-09-14 CN disclosed
CN-105247024-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2018-08-10 CN disclosed
CN-105283529-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2018-08-10 CN disclosed
CN-107109278-A For the sulphonic acid ester for the fluoropolymer seal part compatibility for improving lubricant compositions 巴斯夫欧洲公司 2017-08-29 CN disclosed
CN-107109279-A Allcoxylated amides, ester and antiwear additive in lubricant compositions 巴斯夫欧洲公司 2017-08-29 CN disclosed
US-20090239778-A1 Cleaning Agent HENKEL KGAA (DE) 2009-09-24 US disclosed
CN-1081674-A Sterilant 1,2, the 4-triazole compounds ROHM & HAAS (US) 1994-02-09 CN disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
JP-S6042370-A 3-(1,2,4-TRIAZOLYL-1-YL)-PROP-1-ENE BAYER AG 1985-03-06 JP disclosed
US-4032532-A AZO DYES SANDOZ LTD. (CH) 1977-06-28 US disclosed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US disclosed