SCHEMBL4433240

SCHEMBL4433240

CC1(C)C(C=C(Cl)Cl)C1C(=O)OCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.76
LMNA P02545 4/20 0.76
ATM Q13315 2/20 0.76
ADRA2A P08913 1/20 0.76
CNR1 P21554 1/20 0.76
L3MBTL1 Q9Y468 1/20 0.76
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 3/20 0.53
TSHR P16473 3/20 0.49
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
CYP1A2 P05177 2/20 0.45
CYP2C19 P33261 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
ELANE P08246 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22931582 1.00 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL30603080 1.00 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL4433243 1.00 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL4433235 1.00 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL11419875 0.89 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL9557955 0.89 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL11344968 0.89 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL11624273 0.89 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL523193 0.89 TDP1 (0.76) TDP1LMNAATMADRA2ACNR1
SCHEMBL14157372 0.88 TDP1 (0.61) TDP1LMNAATMADRA2ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025088039-A1 HIGHLY CONCENTRATED DERMALLY APPLICABLE PERMETHRIN PREPARATION WITH AN INCREASED DRUG LOAD IN THE TARGET COMPARTMENT FOR IMPROVED TREATMENT OF ECTOPARASITE INFESTATION INFECTOPHARM ARZNEIMITTEL UND CONSILIUM GMBH (DE) 2025-05-01 WO disclosed
EP-4545067-A1 HIGHY DOSED DERMALLY APPLICABLE PERMETHRIN PREPARATION HAVING AN INCREASED DRUGLOAD IN THE TARGET COMPARTIMENT FOR IMPROVED TREATMENT OF ECTOPARASITE INFESTATION Infectopharm Arzneimittel und Consilium GmbH (DE) 2025-04-30 EP disclosed
US-11119033-B2 Conformation analysis device, analysis method, conformational notation device and notation method Izumi, Hiroshi (JP) 2021-09-14 US disclosed
US-20090248321-A1 Conformation analysis device, analysis method, conformational notation device and notation method IZUMI, HIROSHI (JP) 2009-10-01 US disclosed
US-4999451-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-03-12 US disclosed
US-4833266-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-05-23 US disclosed
US-4681953-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-07-21 US disclosed
US-4500733-A Process for preparing dihalovinylcyclopropanecarboxylic acids SAGAMI CHEMICAL RESEARCHCENTER (JP) 1985-02-19 US disclosed
US-4454343-A Intermediates in a process for preparing dihalovinylcyclopropanecarboxylates FMC CORPORATION (US) 1984-06-12 US disclosed
US-4289711-A Ester synthesis BURROUGHS WELLCOME CO. (US) 1981-09-15 US disclosed
US-4214097-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1980-07-22 US disclosed